Clinical Abstract: Frequency and Distribution of Radiolucent Jaw Lesions: A Retrospective Analysis of 9,723 Cases

Clinical Abstract: Frequency and Distribution of Radiolucent Jaw Lesions: A Retrospective Analysis of 9,723 Cases

T. Koivisto, W.R. Bowles, and M. Rohrer:
 
The following abstract is reprinted with permission from the Journal of Endodontics, June 2012, Volume 38, Number 6, pages 729-32; Epub April 13, 2012.
 
Frequency and Distribution of Radiolucent Jaw Lesions: A Retrospective Analysis of 9,723 Cases
 
Koivisto T, Bowles WR, Rohrer M. Division of Endodontics, University of Minnesota School of Dentistry, Minneapolis, Minnesota 55455. 
 
Abstract
Objectives
Practitioners should be aware of the occurrence rate and usual location of radiolucent jaw lesions. The aims of this study were to examine the frequency and location of radiolucent jaw lesions,  including apical granulomas, apical cysts, keratocystic odontogenic tumors (KOTs), central giant cell lesions (CGCLs), ameloblastomas, and metastatic lesions, that were submitted for biopsy along  with associated demographics.
 
Methods
Biopsy diagnoses from 9,723 lesions (submitted between 1992 and 2006) were included in this study. Data on lesion location as well as patient demographics were evaluated. 
 
Results 
Thirty types of radiolucent jaw lesions were classified.  
Non-healing apical granulomas (40.4%) and cysts (33.1%) occurred at similar rates and together totaled 73% of all biopsied lesions. The majority of reported granulomas and cysts occurred in the  anterior maxilla (>36% in each category). The frequency of KOTs (8.8%), CGCLs (1.3%), ameloblastomas (1.2%), and metastatic lesions (<1%) are to be noted along with their location, which was predominantly in the posterior mandible. The occurrence of apical cysts, ameloblastomas, KOTs, and metastatic lesions were seen slightly more in men, at 56%, 54%, 55%, and 68%, respectively.  The occurrence of CGCLs was seen slightly more in women at 56%, whereas apical granulomas were equally present in men and women. 
 
Conclusions
Most non-healing lesions submitted for biopsy were classified as granulomas or cysts (73%) often from the anterior maxillary jaw. Non-healing radiolucent jaw lesions other than granulomas or cysts  were reported more than 20% of the time and may have more severe pathological implications, suggesting the value of differential diagnoses.